簡(jiǎn)要描述:Human CD4+/CD25+ Regulatory T Cells (Tregs,人CD4+/CD25+調(diào)節(jié)性T細(xì)胞), formerly known as suppressor T cells, are a subpopulation of T cells.
product name:Human CD4+/CD25+ Regulatory T Cells(人CD4+/CD25+調(diào)節(jié)性T細(xì)胞);
cat no:ABC-TC4002;
Size/Quantity:1 vial;
Biosafety Level:1;
Shipping Info:Dry Ice;
Storage:Liquid Nitrogen;
Description:Human CD4+/CD25+ Regulatory T Cells (Tregs,人CD4+/CD25+調(diào)節(jié)性T細(xì)胞), formerly known as suppressor T cells, are a subpopulation of T cells. They are derived from progenitor cells in bone marrow and play an important role in maintaining immune homeostasis. Tregs act by immunosuppression or downregulation of other immune cells, preventing autoimmune disease and chronic inflammation. However, its suppressiveness also limits some beneficial immune responses during microorganism infection and anti-tumor activity. Naturally occurring Tregs (nTregs) express CD4, CD25 and a key transcription factor forkhead box P3 (FOXP3). Human CD4+/CD25+ Regulatory T Cells also downregulate the expression of CD127 (or IL-7R), which can be used as Treg cells marker during identification and purification.;
Quality Control:All cells test negative for mycoplasma, bacteria, yeast, and fungi;
Application:For research use only.